Bind to a Selected Item

RadTreeView exposes SelectedItem property, which is a DependencyProperty and can be used in a data binding.

<telerik:RadTreeView SelectedItem="{Binding SelectedItem, Mode=TwoWay}"/> 

If you want to bind to the RadTreeViewItem's IsSelected property when your treeview is data bound to an object, then you need to use an ItemContainerStyle.

<telerik:RadTreeView> 
    <telerik:RadTreeView.ItemContainerStyle> 
        <Style TargetType="telerik:RadTreeViewItem"> 
            <Setter Property="IsSelected" Value="{Binding Path=Select, Mode=TwoWay}" /> 
        </Style > 
    </telerik:RadTreeView.ItemContainerStyle> 
</telerik:RadTreeView> 

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