No Wrap for Grid Cell Content

This appearance customization is not supported out-of-the-box in the current version of Telerik RadGrid. However, there is a workaround which you can apply to prevent the wrapping for column cells content. Set the DataFormatString property for each column to {0}. Thus the column(s) in your grid instance should stretch to fit the width of the longest text inside the column(s) cells.

For declarative columns the code be as below:

<telerik:RadGrid ID="RadGrid1" runat="server">
  <MasterTableView AutoGenerateColumns="false">
    <telerik:GridBoundColumn UniqueName="ContactName" HeaderText="Contact name" DataField="ContactName"
      DataFormatString="<nobr>{0}</nobr>" />
    <telerik:GridBoundColumn UniqueName="ContactTitle" HeaderText="Contact title" DataField="ContactTitle"
      DataFormatString="<nobr>{0}</nobr>" />
    <telerik:GridBoundColumn UniqueName="CompanyName" HeaderText="Company name" DataField="CompanyName"
      DataFormatString="<nobr>{0}</nobr>" />
    <telerik:GridBoundColumn UniqueName="Country" HeaderText="Country" DataField="Country"
      DataFormatString="<nobr>{0}</nobr>" />
    <telerik:GridBoundColumn UniqueName="City" HeaderText="City" DataField="City" DataFormatString="<nobr>{0}</nobr>" />
  </MasterTableView>
</telerik:RadGrid>

For auto-generated column subscribe to the ColumnCreated event and set the DataFormatString in the corresponding handler:

protected void RadGrid1_ColumnCreated(object sender, GridColumnCreatedEventArgs e)
{
    //add more column types to the conditional check if needed
    if (e.Column is GridBoundColumn)
    {
        (e.Column as GridBoundColumn).DataFormatString = "<nobr>{0}</nobr>";
    }
}
Protected Sub RadGrid1_ColumnCreated(ByVal sender As Object, ByVal e As GridColumnCreatedEventArgs) Handles RadGrid1.ColumnCreated
    'add more column types to the conditional check if needed
    If (TypeOf e.Column Is GridBoundColumn) Then
        CType(e.Column, GridBoundColumn).DataFormatString = "<nobr>{0}</nobr>"
    End If
End Sub

In the code-behind (just data-binding):

private void RadGrid1_NeedDataSource(object source, Telerik.Web.UI.GridNeedDataSourceEventArgs e)
{
    OleDbConnection MyOleDbConnection = new OleDbConnection("Provider=Microsoft.Jet.OLEDB.4.0; Data Source=" + Server.MapPath("~/Grid/Data/Access/Nwind.mdb"));
    OleDbDataAdapter MyOleDbDataAdapter = new OleDbDataAdapter();
    MyOleDbDataAdapter.SelectCommand = new OleDbCommand("SELECT TOP 10 CompanyName, ContactName, ContactTitle, Country, City FROM Customers", MyOleDbConnection);
    DataTable myDataTable = new DataTable();
    MyOleDbConnection.Open();
    try
    {
        MyOleDbDataAdapter.Fill(myDataTable);
    }
    finally
    {
        MyOleDbConnection.Close();
    }
    RadGrid1.DataSource = myDataTable.DefaultView;
}
Private Sub RadGrid1_NeedDataSource(ByVal [source] As Object, ByVal e As Telerik.Web.UI.GridNeedDataSourceEventArgs) Handles RadGrid1.NeedDataSource
    Dim MyOleDbConnection As New OleDbConnection("Provider=Microsoft.Jet.OLEDB.4.0; Data Source=" + Server.MapPath("~/Grid/Data/Access/Nwind.mdb"))
    Dim MyOleDbDataAdapter As New OleDbDataAdapter()
    MyOleDbDataAdapter.SelectCommand = New OleDbCommand("SELECT TOP 10 CompanyName, ContactName, ContactTitle, Country, City FROM Customers", MyOleDbConnection)

    Dim myDataTable As New DataTable()

    MyOleDbConnection.Open()
    Try
        MyOleDbDataAdapter.Fill(myDataTable)
    Finally
        MyOleDbConnection.Close()
    End Try

    RadGrid1.DataSource = myDataTable.DefaultView
End Sub
note

This functionality is not supported with static headers (UseStaticHeaders = true) and column resizing. With static headers the cell content will be clipped if you resize a column to make its width dimension smaller than the longest cell data.